Propolis side effects diarrhea

Propolis is a mixture of pollen and beeswax collected by bees from certain plants and trees.

Metrics details. Brazilian green propolis is reported to have wide range of biological properties including antibacterial, anti-inflammatory, anti-influenza, and antioxidant activities. In the digestive system, a protective effect of propolis on gastric ulcer has been reported, but a laxative effect has not yet been reported. We investigated the effect and the mechanism of action of water and ethanol extracts of Brazilian green propolis. We also investigated the effects of WEP on gastrointestinal transit and contractional tension of the ileum to uncover the mechanism of action of WEP. WEP treatment significantly restored stool frequency and stool weight in clonidine-induced constipation model mice, but not in loperamide-induced constipation model mice.

Propolis side effects diarrhea

Federal government websites often end in. The site is secure. There are a number of disorders that affect the gastrointestinal tract. Such disorders have become a global emerging disease with a high incidence and prevalence rates worldwide. Inflammatory and ulcerative processes of the stomach or intestines, such as gastritis, ulcers, colitis, and mucositis, afflict a significant proportion of people throughout the world. The role of herbal-derived medicines has been extensively explored in order to develop new effective and safe strategies to improve the available gastrointestinal therapies that are currently used in the clinical practice. Studies on the efficacy of propolis a unique resinous aromatic substance produced by honeybees from different types of species of plants are promising and propolis has been effective in the treatment of several pathological conditions. This review, therefore, summarizes and critiques the contents of some relevant published scientific papers including those related to clinical trials in order to demonstrate the therapeutic value of propolis and its active compounds in the treatment and prevention of gastrointestinal diseases. Honey bees produce it by mixing their saliva and beeswax with the exudates obtained from plants like tree buds, sap flows, leaves, branches, and barks of plants found in the vicinity of the beehive. The ultimate goal of propolis is for bees to protect their hives by utilizing it to seal cracks and protect bees from predators and microorganisms and provide thermal insulation [ 1 — 3 ]. The term propolis has originated from Greek word pro, for or in defense of, and polis, the city [ 1 ]. The color of propolis is variable and depends on the plants' type that the bees used to collect the resinous substances. Three main colors have been noted: green, red, brown, or black propolis [ 4 ]. For instance, the red propolis from Cuba or Venezuela has botanical origins identified as Clusia nemorosa Forsteronia G.

WEP treatment significantly restored stool frequency and stool weight in clonidine-induced constipation model mice, but not in loperamide-induced constipation model mice.

Federal government websites often end in. The site is secure. Brazilian green propolis is reported to have wide range of biological properties including antibacterial, anti-inflammatory, anti-influenza, and antioxidant activities. In the digestive system, a protective effect of propolis on gastric ulcer has been reported, but a laxative effect has not yet been reported. We investigated the effect and the mechanism of action of water and ethanol extracts of Brazilian green propolis.

Propolis is a mixture of pollen and beeswax collected by bees from certain plants and trees. Rich in flavonoids , a class of antioxidants, propolis has a long history of use as a natural treatment for many health problems, but more research is needed in humans to support its use. Although found in small quantities in honey, propolis is also widely available in supplement form. For example, propolis is used as an ingredient in certain products applied directly to the skin, such as ointments and creams. In addition, propolis is sometimes found in nasal sprays and throat sprays, as well as in mouthwash and toothpaste. This article discusses the potential uses of propolis. It also covers the risk factors and side effects of taking this supplement.

Propolis side effects diarrhea

Federal government websites often end in. The site is secure. Propolis is a beekeeping product with a complex and highly variable chemical composition. Many beneficial health properties have been reported. In this review, we will be focusing on compiling the studies carried out with propolis on infectious diseases of greater medical relevance.

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Anti-Cancer Drugs. Such disorders have become a global emerging disease with a high incidence and prevalence rates worldwide. The extract also showed cytotoxic in HEp-2, human laryngeal epidermoid carcinoma [ ]. See Our Editorial Process. Omene C. Up to this point, the reviewed studies have evaluated the antiulcer protective effects of propolis preparations. Third european evidence-based consensus on diagnosis and management of ulcerative colitis. Kaempferol is another flavonoid ingredient of propolis inducing apoptosis through activation of TNF-related apoptosis-inducing ligand TRAIL in SW cells, a human colon cancer [ ], and inhibiting ribosomal protein S6 kinase RSK2 and mitogen- and stress-activated kinase MSK1 , main regulators in tumor promoter induced cell transformation [ ]. Abraham C. If these effects persist or worsen, contact your doctor promptly. Antihypertensive effects of flavonoids isolated from brazilian green propolis in spontaneously hypertensive rats. Chemopreventive action by ethanol-extracted brazilian green propolis on post-initiation phase of inflammation-Associated rat colon tumorigenesis. MacPherson B. Therefore, the geographical location, plant sources, collection season, bee species, and solvents used in the extraction have an influence on the chemical composition and on the pharmacological activity of propolis preparation. I suspect this is from the many web sites out there who claim to be experts on bee pollen but are really just 'no bodies' pushing a bee pollen product through a referral program.

Federal government websites often end in. The site is secure.

Purported propolis benefits are varied. Three main colors have been noted: green, red, brown, or black propolis [ 4 ]. Zeitschrift fur Naturforschung C, Journal of biosciences. Azuma T. Comparison of bee products based on assays of antioxidant capacities. Such disorders have become a global emerging disease with a high incidence and prevalence rates worldwide. These stimulant-type agents often induce diarrheas as adverse effects at common doses[ 32 , 33 ]. Similar to the other flavonoids ingredients, quercetin exhibits anticancerous properties through stimulation of apoptotic pathways. Jakobsson H. Abraham C. Originally written by Cathy Wong. There are a number of disorders that affect the gastrointestinal tract. We examined with two different Lots of WEP and got almost the same result. Caffeic acid phenethyl ester inhibits invasion and expression of matrix metalloproteinase in SK-Hep1 human hepatocellular carcinoma cells by targeting nuclear factor kappa B.