J affect disord

The Journal of Affective Disorders is a peer-reviewed medical journal covering research on all aspects of affective disorders. It is published by Elsevier and its editors-in-chief are P.

Giada Benasi , Giovanni A. Psychother Psychosom 11 October ; 90 6 : — Introduction : Appraisal of prodromal symptoms of unipolar depression may complement the traditional cross-sectional approach and provide a longitudinal perspective, according to a staging model of the illness. Objective: To provide an updated systematic review of clinical studies concerned with prodromal symptoms of unipolar depression, according to PRISMA guidelines. Longitudinal studies on prodromal symptoms and signs in adult patients primarily diagnosed with unipolar depression were selected. Findings were examined separately according to study design i. Results: Twenty-five studies met the criteria for inclusion in this systematic review.

J affect disord

Federal government websites often end in. The site is secure. The COVID outbreak has brought tremendous psychological pressure to the general population, which may lead to depression. Therefore, this study aim to evaluate the prevalence and clinical correlates of depressive symptoms in the general population quarantined during the COVID outbreak in Shenzhen. The prevalence of depressive symptom was 6. This study adopted a cross-sectional design and used self-report questionnaires. Our results suggest an elevated prevalence of depressive symptom in quarantined general individuals in Shenzhen. Some demographic and clinical variables were associated with depressive symptoms. Since the December of , Novel Coronavirus Pneumonia COVID infection has broken out in China, resulting in more than 80, infections and more than deaths there, and a huge number of people have been quarantined. The rapid spread and high mortality of COVID seriously threaten people's physical and mental health, and cause a series of mental diseases such as depression, post-traumatic stress disorder, anxiety, and panic disorder. According to previous studies, depression is one of the most common mental disorders triggered by emerging infectious disease EID Mak et al. Recent studies have shown that during the COVID outbreak, the depression rate in the general population ranges from 3. Without early intervention, these depressive symptoms may develop into long-term depression Lee et al. For example, Lee et al.

In both studies [ 17, 18 ] the relationship between residual and prodromal symptoms was specifically addressed.

The association of major depressive disorders with personality disorders is relevant in terms of clinical, therapeutic and prognostic aspects. However, the prevalence of this association remains unclear. This may be due to methodological considerations. The prevalence of personality disorders among patients with a lifetime major depression has been insufficiently studied, although it may concern half of these patients. The prevalence of current of lifetime major depression among patients with a personality disorder has not been sufficiently studied and results are very scattered. Also, the coexistence of personality disorder and major depression is frequent, and this review emphasizes the heterogeneity of the personality styles associated with major depression.

Background: As a major virus outbreak in the 21st century, the Coronavirus disease COVID pandemic has led to unprecedented hazards to mental health globally. While psychological support is being provided to patients and healthcare workers, the general public's mental health requires significant attention as well. This systematic review aims to synthesize extant literature that reports on the effects of COVID on psychological outcomes of the general population and its associated risk factors. A manual search on Google Scholar was performed to identify additional relevant studies. Articles were selected based on the predetermined eligibility criteria. Results: Relatively high rates of symptoms of anxiety 6. Limitations: A significant degree of heterogeneity was noted across studies. Conclusions: The COVID pandemic is associated with highly significant levels of psychological distress that, in many cases, would meet the threshold for clinical relevance. Mitigating the hazardous effects of COVID on mental health is an international public health priority.

J affect disord

Objective: To compare the efficacy and discontinuation of augmentation agents in adult patients with treatment-resistant depression TRD. We conducted a systematic review and network meta-analyses NMA to combine direct and indirect comparisons of augmentation agents. Methods: We included randomized controlled trials comparing one active drug with another or with placebo following a treatment course up to 24 weeks. Nineteen agents were included: stimulants, atypical antipsychotics, thyroid hormones, antidepressants, and mood stabilizers. We estimated effect-size by relative risk using pairwise and NMA with random-effects model. Our findings from the NMA for response rates, compared to placebo, were significant for: liothyronine, nortriptyline, aripiprazole, brexpiprazole, quetiapine, lithium, modafinil, olanzapine fluoxetine , cariprazine, and lisdexamfetamine. For remission rates, compared to placebo, were significant for: thyroid hormone T4 , aripiprazole, brexpiprazole, risperidone, quetiapine, and olanzapine fluoxetine. Compared to placebo, ziprasidone, mirtazapine, and cariprazine had statistically significant higher discontinuation rates. Limitations: Heterogeneity in TRD definitions, variable trial duration and methodological clinical design of older studies and small number of trials per comparisons. Conclusions: This NMA suggests a superiority of the regulatory approved adjunctive atypical antipsychotics, thyroid hormones, dopamine compounds modafinil and lisdexamfetamine and lithium.

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The mental health assessment questionnaire was delivered to the subjects face to face by the epidemiological investigation team. According to the Journal Citation Reports , the journal has a impact factor of 6. Validation of the Zung self-rating depression scale SDS in older adults. Sleep Med. First, this is a cross-sectional design study that does not show a causal relationship between depression and related clinical factors. Several limitations of this study should be noted. Such a perspective paves the way for the development of clinical staging in psychiatry [ 2 ]. The prevalence of depressive symptom was 6. Our investigation period corresponded to the debilitating stage after the largest outbreak of COVID epidemic in China Shen et al. Download as PDF Printable version. Results 3. All p values were 2 tails, reaching a significant level of 0. Also, 18 elderly people over 70 years old were excluded because of potential cognitive impairment. All authors contributed to and approved the final manuscript.

Federal government websites often end in. The site is secure. Suicide is a preventable cause of death, yet every 40 seconds someone dies by suicide resulting in about , suicide deaths each year across the globe WHO,

Detection of prodromal symptoms of relapse in mania and unipolar depression by relatives and patients. Further, the identification of prodromal symptomatology might throw some light on the longitudinal development and course of late-onset depression. You can help Wikipedia by expanding it. In both studies, the median speed of onset was significantly higher among patients with unipolar MDD than in those with bipolar disorder [ 11, 12 ]. In conclusion, our results show that the prevalence rate of depressive symptoms in the quarantined individuals was 6. Journal Section:. For example, a study in Toronto reported that the prevalence of depressive symptoms among quarantined individuals during SARS was Qiwen Deng: moc. We should pay more attention to PTSS, especially avoidance symptoms and hyperarousal symptoms. Therefore, these findings suggest that depression and PTSS are mutually predictive variables. The mental health assessment questionnaire was delivered to the subjects face to face by the epidemiological investigation team.