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Acetaminophen and oxycodone is a combination medicine used to relieve moderate to severe pain.

Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed milligrams per day, and often involve more than one acetaminophen-containing product. Each tablet, for oral administration, contains oxycodone hydrochloride and acetaminophen in the following strengths:. All strengths of oxycodone and acetaminophen tablets USP also contain the following inactive ingredients: crospovidone, microcrystalline cellulose, povidone, pregelatinized starch, silicon dioxide and stearic acid. It is derived from the opium alkaloid thebaine. Oxycodone hydrochloride may be represented by the following structural formula:. Acetaminophen, 4'-hydroxyacetanilide, is a non-opiate, non-salicylate analgesic and antipyretic which occurs as a white, odorless, crystalline powder, possessing a slightly bitter taste.

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Acetaminophen belongs to a group of medicines called analgesics pain relievers and antipyretics fever reducers. It works quickly to relieve pain caused by conditions such as headache and osteoarthritis, and to reduce fever caused by infection. Unlike acetylsalicylic acid ASA , which is also an analgesic and antipyretic, acetaminophen does not reduce inflammation. Acetaminophen is used by itself as well as in combination medication products for cough, cold, and pain relief. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it. For brands that may still be available, search under acetaminophen. This article is being kept available for reference purposes only. If you are using this medication, speak with your doctor or pharmacist for information about your treatment options.

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If you are a consumer or patient please visit this version. Liver warning: This product contains acetaminophen. Severe liver damage may occur if. Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:. Do not use with any other drug containing acetaminophen prescription or nonprescription.

Acetaminophen and oxycodone is a combination medicine used to relieve moderate to severe pain. Acetaminophen and oxycodone may also be used for purposes not listed in this medication guide. Acetaminophen and oxycodone contains an opioide medicine and may be habit-forming. You should not use this medicine if you are allergic to acetaminophen or oxycodone, or if you have:. If you use opioid medicine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on opioids may need medical treatment for several weeks.

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It is available as a prescription only medicine and is commonly used for Chronic Pain, Pain. Exercise has many benefits for older adults and can help you to live a longer and healthier life. Here are 6 benefits of exercise for older adults and seniors. Natural home remedies and over-the-counter OTC products can be used to temporarily relieve toothache pain until you can visit your dentist. Certain over-the-counter pain medications can be used alongside antibiotics and other self care options to help alleviate the pain caused by a UTI. CBD cannabidiol is a chemical found in the Cannabis sativa plant, which is being investigated for its potential health benefits.

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After birth, the neonate may suffer severe withdrawal symptoms. Follow your doctor's instructions about tapering your dose. Respiratory depression is a hazard with the use of oxycodone, one of the active ingredients in oxycodone and acetaminophen tablets, as with all opioid agonists. Mallinckrodt Inc. Instead, they must consult with their prescribing physician. You should not stop using this medicine suddenly. Patients receiving other opioid analgesics, general anesthetics, phenothiazines, other tranquilizers, centrally-acting anti-emetics, sedative-hypnotics or other CNS depressants including alcohol concomitantly with oxycodone and acetaminophen tablets may exhibit an additive CNS depression. This could occur even if you have taken acetaminophen in the past and had no reaction. Although oxycodone may cross-react with some drug urine tests, no available studies were found which determined the duration of detectability of oxycodone in urine drug screens. Selecting these links will take you away from Cigna. Common Name:. Check the product label on all medications you are taking to make sure you are not exceeding the recommended dose of acetaminophen. Find a Doctor. Do not take more than milligrams of acetaminophen per day. Acetaminophen and oxycodone contains an opioide medicine and may be habit-forming.

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Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. This should be considered when prescribing or dispensing oxycodone and acetaminophen tablets in situations where the physician or pharmacist is concerned about an increased risk of misuse, abuse, or diversion. Oxycodone is an opioid agonist of the morphine-type. Oxygen, intravenous fluids, vasopressors, and other supportive measures should be employed as indicated. If you develop signs of allergy such as a rash or difficulty breathing stop taking oxycodone and acetaminophen tablets USP and contact your healthcare provider immediately. Call your doctor at once if you have: Opioid medicine can slow or stop your breathing, and death may occur. There may be an interaction between acetaminophen and any of the following: alcohol benzocaine benzydamine busulfan carbamazepine chloramphenicol dapsone dasatinib fosphenytoin imatinib ipilimumab isoniazid lamotrigine lidocaine phenobarbital phenylephrine phenytoin pramoxine prilocaine primidone probenecid rifampin sorafenib tetracaine vaccines warfarin If you are taking any of these medications, speak with your doctor or pharmacist. An overdose can damage your liver or cause death. Keep track of your medicine. Children should not take more than 5 doses in 24 hours unless advised by a doctor.