Rime medical abbreviation

The RIME framework provides terminology for describing the professional growth of medical students.

RIME is characterized by prominent mucositis, usually with sparse or even absent cutaneous involvement. This topic will discuss the pathogenesis, clinical manifestations, diagnosis, and treatment of RIME. Based on the subsequent observation that other bacterial and viral respiratory infections can cause a mucocutaneous reaction in children, it has been proposed that MIRM should be included in a broader category called "reactive infectious mucocutaneous eruption" RIME. RIME describes mucocutaneous eruptions resulting from a variety of infectious triggers and differentiates infectious triggers, which are far more likely in children and adolescents, from drug triggers [ ]. RIME most often occurs during winter [ 25 ]. Children serve as the primary reservoir for M.

Rime medical abbreviation

Previously, M. Mycoplasma pneumoniae M. The precise pathophysiology of MIRM is not completely understood. One proposed mechanism is polyclonal B-cell proliferation and antibody production with subsequent immune complex deposition and complement activation that could cause skin damage. Another possibility is molecular mimicry between Mycoplasma P1-adhesion molecules and a host's keratinocytes. MIRM typically affects younger patients with a slight male predominance. Patients generally have a prodrome of fever, malaise, and cough approximately one week prior to the onset of mucocutaneous eruption. MIRM is a diagnosis made by a combination of clinical, radiographic, and laboratory findings, and does require a high level of suspicion. Most patients are seen in the inpatient setting; therefore, the exam can be performed with an indirect ophthalmoscope, 20 diopter lens, fluorescein stain, and cobalt blue light source to evaluate the anterior segment. A thorough evaluation of the cornea, conjunctiva bulbar and palpebral , and eyelids including mucocutaneous junction is necessary to evaluate the extent of ocular involvement. One must assess for the presence of epithelial sloughing as evidenced by fluorescein staining on the above surfaces. MIRM features a prominent mucositis and almost always has oral involvement that can be in the form of vesiculobullous lesions and extensive erosions Figure 1. Ocular symptoms are not as well described in the current literature, but can include redness, tearing, photophobia, and blurry vision. The diagnosis of MIRM depends on the typical features as described above and evidence of recent infection with M.

Ocul Surf ; See "Erythema multiforme: Pathogenesis, clinical features, and diagnosis", rime medical abbreviation. In a review of published cases from tothe mortality rate was 3 percent, and all deaths occurred in the s [ 4 ].

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This topic will discuss the pathogenesis, clinical manifestations, diagnosis, and treatment of RIME. Why UpToDate? Learn how UpToDate can help you. Select the option that best describes you. View Topic. Font Size Small Normal Large. Reactive infectious mucocutaneous eruption RIME. Formulary drug information for this topic. No drug references linked in this topic.

Rime medical abbreviation

Reactive infectious mucocutaneous eruption RIME was recently proposed to replace the term Mycoplasma pneumoniae MP -induced rash and mucositis to account for the fact that non-MP pathogens may also cause rash and mucositis. In this report, we describe a unique case of recurrent RIME featuring a total of three episodes. As two of the episodes demonstrated contemporaneous infection with MP and group A streptococcus or influenza B, this case lends further support to use of the term RIME. In addition, although RIME typically involves at least two mucous membranes, this case shows that recurrent episodes may fall into the rare exception in which mucositis is limited to one site. Keywords: Mycoplasma pneumoniae; Mycoplasma pneumoniae-induced rash and mucositis; coinfection; group A streptococcus; influenza B; reactive infectious mucocutaneous eruption; recurrence. Abstract Reactive infectious mucocutaneous eruption RIME was recently proposed to replace the term Mycoplasma pneumoniae MP -induced rash and mucositis to account for the fact that non-MP pathogens may also cause rash and mucositis. Publication types Case Reports.

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Search the web. Pediatr Neonatol ; So many questions need to be answered. Because many of our dermatological diseases affect relatively small numbers of patients and have overlapping features and tangled case definitions, real opportunities exist to move our understanding of disease forward. Please reload this page and sign into VisualDx to continue. Start your 7 day free trial. Other immunomodulatory therapies — Other immunomodulatory treatments that have been reported in cases of RIME with severe mucosal involvement include cyclosporine [ 65 ], intravenous immune globulin IVIG [ 66 ], and anti-tumor necrosis factor TNF agents [ 67,68 ]. Epub Mar As an example, molecular mimicry between M. Eur J Clin Microbiol ; Lane MD Antoinette L. Because of the distinct morphology, mild disease course, and potential clinical implications regarding treatment, the authors proposed revising nomenclature, suggest the term MIRM for these cases. Uptodate Reference Title. Approximately 4 percent of patients with RIME require intensive care [ 4 ].

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For example: 'VisualDx,' 'password,' and other passwords commonly found in data breaches. Diagn Microbiol Infect Dis. The Gregory guidelines for treatment of SJS categorize patients into mild, moderate, severe, and extremely severe based on the location and extent of conjunctival and corneal epithelial sloughing. DIAGNOSIS — RIME should be suspected in a child or young patient presenting with a mucosal or mucocutaneous eruption and a history of prodromal symptoms, including cough, malaise, and fever, preceding the eruption by approximately one week [ 4 ]. Laboratory findings — Patients with RIME often have elevated acute phase reactants, including C-reactive protein and erythrocyte sedimentation rate [ 27 ]. Filter by: Select category from list Immunological interactions between host cells and mycoplasmas: an introduction. Open Forum Infect Dis ; 7:ofaa Research and Innovations in Medical Education Medical -- and more Saline rinses and multiple daily applications of ocular lubricants are indicated for patients with mild conjunctivitis. Rabinovitz MD Christopher J. Reactive infectious mucocutaneous eruption in Adult. Constitutional symptoms, such as fever, are common and may precede the onset of the disease. Clinicians, however, need to make observations, publish case series, and get feedback from colleagues through published literature, presentations, and shared experiences to define and redefine emerging conditions over time.