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Federal government websites often end in, lee vrac. The site is secure. The original lee vrac presented in the study are included in the article, further inquiries can be directed to the corresponding author. Objective: In this study, we utilized bibliometric methods to assess the worldwide scientific output and identify hotspots related to modaselvim sandalet research on the volume-regulated anion channel VRAC from to

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Lee vrac

Objective: In this study, we utilized bibliometric methods to assess the worldwide scientific output and identify hotspots related to the research on the volume-regulated anion channel VRAC from to To analyzed the data, we utilized VOSviewer, a tool for visualizing network, to create networks based on the collaboration between countries, institutions, and authors. Additionally, we performed an analysis of journal co-citation, document citation, and co-occurrence of keywords. Furthermore, we employed CiteSpace 6. R6 Advanced to analyzed keywords and co-cited references with the strongest burst. Results: The final analysis included a total of related articles and reviews, covering the period from to The United States emerged as the leading country contributing to this field, while the University of Copenhagen stood out as the most prominent institution. The author with most publications and most citations was Thomas J. Among the cited references, the article by Voss et al. Through the analysis of keyword co-occurrence, it was discovered that VRAC is involved in various physiological processes including cell growth, migration, apoptosis, swelling, and myogenesis, as well as anion and organic osmolyte transport including chloride, taurine, glutamate and ATP. VRAC is also associated with related ion channels such as TMEM16A, TMEM16F, pannexin, and CFTR, and associated with various diseases including epilepsy, leukodystrophy, atherosclerosis, hypertension, cerebral edema, stroke, and different types of cancer including gastric cancer, glioblastoma and hepatocellular carcinoma. Furthermore, VRAC is involved in anti-tumor drug resistance by regulating the uptake of platinum-based drugs and temozolomide. Conclusion: The aim of this bibliometric analysis is to provide an overall perspective for research on VRAC. VRAC has become a topic of increasing interest, and our analysis shows that it continues to be a prominent area. This study offers insights into the investigation of VRAC channel and may guide researchers in identifying new directions for future research.

Regarding the number of citations, publications originating from the United States garnered the most citations, totaling 2, followed by Germany with citations, Switzerland with citations, Italy with citations, and Japan with citations Figure 3B. Zhou, P. Bertelli and others have recently discovered that oxidation targets two cysteines, namely, C and C, lee vrac, which are situated in lee vrac initial two leucine rich repeats of LRRC8E.

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Surprisingly, the excessive expression of functional LRRC8 heteromers does not lead to an elevation of VRAC currents beyond the levels observed in the endogenous state. Immunity 52 , — Next, we conducted an analysis of 72 journals based on their co-citation frequency in over 50 publications Figure 5. JCI Insight 3, e Based on our current understanding, this study represents the initial bibliometric analysis examining patterns in VRAC channel research area. These mice showed significantly reduced the volume of brain infarct and improved the score of neurological severity in a stroke model known as temporal middle cerebral artery occlusion tMCAO , indicating that VRAC channel in astrocytes is indeed participated in brain damage which induced by stroke in vivo Yang et al. Ion channels: Functional expression and therapeutic potential in cancer: Colloquium on ion channels and cancer. PPExMed 1, 3— Database collection and results interpretation: TL, YL. Elife 12 , e Syeda et al. However, it is important to acknowledge the limitations of our analysis. TABLE 3. The use, distribution or reproduction in other forums is permitted, provided the original author s and the copyright owner s are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. These two publications separately discovered the genes responsible for encoding VRAC.

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Siemer, S. Ion channels: Functional expression and therapeutic potential in cancer: Colloquium on ion channels and cancer. LRRC8 channel activation and reduction in cytosolic chloride concentration during early differentiation of C2C12 myoblasts. Physiology of cell volume regulation in vertebrates. Functional significance of cell volume regulatory mechanisms. The utilization of keyword co-occurrence analysis enables the identification of emerging research patterns and focal points within a particular research field, offering valuable support for scientific research. Regarding the number of citations, publications originating from the United States garnered the most citations, totaling 2,, followed by Germany with citations, Switzerland with citations, Italy with citations, and Japan with citations Figure 3B. Additionally, it maintains the top rank in country-based co-authorship, indicating its significant contribution and collaborative efforts in advancing the field. In terms of citation analysis and co-cited of references, it has been revealed that the seminal works published by Voss et al. Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus. Swelling-induced chloride current in glioblastoma proliferation, migration, and invasion. The size of the node indicates the number of publications. By utilizing these analytical techniques, we aimed to not only describe the existing landscape but also predict the future research interests and hot topics that are likely to continue garnering attention in the VRAC field.