Granisetron hydrochloride syrup uses

Information about Granisetron Granisetron Uses Granisetron is used to prevent nausea and vomiting due to chemotherapy. How Granisetron works Granisetron is an antiemetic medication.

Chemotherapy-induced nausea and vomiting CINV , prevention:. Highly emetogenic chemotherapy:. Moderately emetogenic chemotherapy:. Low-emetogenic chemotherapy:. Consult drug interactions database for more information.

Granisetron hydrochloride syrup uses

Granisetron is a serotonin 5-HT 3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy and radiotherapy. Its main effect is to reduce the activity of the vagus nerve , which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors. Granisetron was developed by chemists working at the British drug company Beecham c. It is produced by Roche Laboratories under the trade name Kytril. It was patented in and approved for medical use in It may be used for chemotherapy -induced nausea and vomiting and appears to work about the same as ondansetron. This is one type of drug that a doctor can prescribe to prevent, lessen, or relieve discomfort. A number of medications including granisetron appear to be effective in controlling post-operative nausea and vomiting PONV. The granisetron patch Sancuso has been studied for use in gastroparesis , [7] though it is not FDA approved for this indication. Granisetron is a well-tolerated drug with few side effects. Headache, dizziness, and constipation are the most commonly reported side effects associated with its use.

Panobinostat: Granisetron may enhance the arrhythmogenic effect of Panobinostat. Patch, Transdermal: Sancuso: 3.

Official websites use. Share sensitive information only on official, secure websites. Granisetron is used to prevent nausea and vomiting caused by cancer chemotherapy and radiation therapy. Granisetron is in a class of medications called 5-HT 3 receptor antagonists. It works by blocking serotonin, a natural substance in the body that causes nausea and vomiting. Granisetron comes as a tablet to take by mouth.

Official websites use. Share sensitive information only on official, secure websites. Granisetron is used to prevent nausea and vomiting caused by cancer chemotherapy and radiation therapy. Granisetron is in a class of medications called 5-HT 3 receptor antagonists. It works by blocking serotonin, a natural substance in the body that causes nausea and vomiting. Granisetron comes as a tablet to take by mouth. When taken to prevent nausea and vomiting caused by chemotherapy, granisetron is usually taken 1 hour before chemotherapy is begun. A second dose may be taken 12 hours after the first dose depending on the strength. When taken to prevent nausea and vomiting caused by radiation, granisetron is usually taken within 1 hour before treatment.

Granisetron hydrochloride syrup uses

This page contains brief information about granisetron and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials. FDA label information for this drug is available at DailyMed. Granisetron is approved to be used alone or with other drugs to prevent:.

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Keep patch in original packaging until immediately prior to use. By mouth , intravenous , transdermal. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Add 20 mL of the chosen vehicle and mix to a uniform paste; transfer to a calibrated bottle. Patients with additional risk factors for QTc prolongation may be at even higher risk. Share sensitive information only on official, secure websites. Cardiovascular: Asystole Al Harbi , bradycardia Al Harbi , chest pain, palpitations, sick sinus syndrome. Contact sensitivity to Tween 80 in a child. Saudi Journal of Anaesthesia. What side effects can this medication cause?

Granisetron is a serotonin 5-HT 3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy and radiotherapy. Its main effect is to reduce the activity of the vagus nerve , which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much effect on vomiting due to motion sickness.

Saudi Journal of Anaesthesia. Pharmacodynamics of transdermal granisetron in women with nausea and vomiting of pregnancy. Chemotherapy-induced nausea and vomiting, prevention: High-dose chemotherapy with stem or bone marrow transplant Ref :. For additional information see "Granisetron: Drug information" and see "Granisetron: Patient drug information" For abbreviations, symbols, and age group definitions used in Lexicomp show table. Postradiation days: IV off label , Oral: The appropriate duration of therapy following radiotherapy days is not well defined; ASCO guidelines recommend continuing granisetron once daily on the day after each day of radiation Ref. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. SS has also been reported following overdose of another 5-HT 3 receptor antagonist. Transdermal Sancuso : Apply patch by pressing down firmly to clean, dry, nearly hairless, intact skin on upper outer arm; smooth down with fingers. IV, Oral, Transdermal: No dosage adjustment necessary.