Ecog-acrin cancer research group

Featured Trial Stomach Cancer Treatment. Featured Trial Kidney Cancer Treatment.

Analysis of a Phase II trial for non-small cell lung cancer has suggested neoadjuvant nivolumab improved five-year recurrence-free survival compared with historical outcomes. All rights reserved. Website development by e-Motive Media Limited. This website uses cookies to improve your experience while you navigate through the website. These cookies will be stored in your browser only with your consent.

Ecog-acrin cancer research group

Background: Studies suggest that adjuvant chemotherapy should be initiated at the earliest possible time. Patients and methods: This phase III trial randomized patients to receive continuous infusional 5-FU for 7 days starting within 24 h after curative resection arm A or no perioperative 5-FU arm B. Patients with Dukes' B3 and C disease received adjuvant chemotherapy per standard of care. The primary endpoint of the trial was overall survival in patients with Dukes' B3 and C disease. The secondary objective was to determine whether a week of perioperative infusion would affect survival in patients with Dukes' B2 colon cancer with no additional chemotherapy. Results: From August to May , patients were enrolled and randomized arm A: ; arm B: The trial was terminated early due to slow accrual. The median follow-up is Among patients with Dukes' B3 and C disease, there was no statistically significant difference in OS [median For patients with Dukes' B2 disease, there was also no significant difference in OS median There was no difference between treatment arms in operative complications.

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Federal government websites often end in. The site is secure. Medical decisions made by oncology clinicians have serious implications, even when made collaboratively with the patient. In-depth interviews were conducted with oncology clinicians to ascertain factors that they felt were important while making treatment-related decisions. Basic and global themes were generated following qualitative data analysis. Quantitative results showed that there was poor agreement in ECOG rating between raters. Overall concordance with the gold standard rating ranged between Decision-making in oncology is complex, multifactorial and is influenced by rater and patient-related factors. Decision-making in oncology is often difficult and is influenced by patient preferences, availability and affordability of viable treatment options, views of the treating clinicians and also cultural factors [ 1 ]. There can be complex social and ethical dilemmas that need to be tackled when making treatment decisions [ 2 ].

Ecog-acrin cancer research group

Our network of member institutions is a core component of the organization and our three scientific programs: Therapeutic Studies, Biomarker Sciences, and Cancer Control and Outcomes. The flexible structure of ECOG-ACRIN's membership program has resulted in a large network that provides substantial capabilities for the Group to carry out innovative research, whether in the form of a small, focused study at a single site or a large-scale population-based trial across multiple institutions. They have broad experience in clinical research disciplines and translational science. In clinical research, therapeutic and medical imaging disciplines include medical, surgical, and radiation oncology; hematology; radiology; nuclear medicine; internal medicine; and preventive medicine. In translational science, disciplines include laboratory-based pathology, genetics, molecular biology, and experimental imaging. Related disciplines include statistics, bioinformatics, clinical psychology, behavioral sciences, epidemiology, and health services.

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Featured Trial Stomach Cancer Treatment.

This cookie is set by Youtube and is used to track the views of embedded videos. The trial was terminated early due to slow accrual. Among patients with Dukes' B3 and C disease, there was no statistically significant difference in OS [median Through our member sites, we are pursuing a robust clinical and translational research portfolio that focuses on precision oncology, immunotherapy, reducing over-treatment and over-diagnosis, leveraging novel biomarker platforms to inform therapeutic decision-making, and advancing standards of care in broad populations of cancer patients and those at risk. Necessary cookies are absolutely essential for the website to function properly. Resources for Active Trials. This cookie is set by Google Analytics and is used to store information of how visitors use a website and helps in creating an analytics report of how the website is doing. This cookie is set by Litespeed Server and allows the server to store settings to help improve performance of the site. Advertising and targeting cookies help us provide our visitors with relevant ads and marketing campaigns. This cookie is set by Advanced Ads and measures the browser width. We embed videos from our official Vimeo channel.