Dehp full form
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Di 2-ethylhexyl phthalate DEHP is a man-made chemical. It is a colorless liquid with a slight odor. DEHP is found throughout the environment at low levels. It gets into the environment mostly through the disposal of plastic waste in landfills. Most DEHP in the environment is found in sediments and soil. It sticks strongly to soil and breaks down slowly when it is near the surface. Indoors, DEHP can also stick to dust particles.
Dehp full form
DEHP is the most common member of the class of phthalates , which are used as plasticizers. It is the diester of phthalic acid and the branched-chain 2-ethylhexanol. This colorless viscous liquid is soluble in oil, but not in water. Di 2-ethylhexyl phthalate is produced commercially by the reaction of excess 2-ethylhexanol with phthalic anhydride in the presence of an acid catalyst such as sulfuric acid or para -toluenesulfonic acid. It was first produced in commercial quantities in Japan circa and in the United States in DEHP has two stereocenters, [8] located at the carbon atoms carrying the ethyl groups. As a result, it has three distinct stereoisomers, [8] consisting of an R , R form, an S , S form diastereomers , and a meso R , S form. As most 2-ethylhexanol is produced as a racemic mixture, commercially-produced DEHP is therefore almost always racemic as well, and consists of equal amounts of all three stereoisomers. It is also used as a hydraulic fluid and as a dielectric fluid in capacitors. DEHP also finds use as a solvent in glowsticks.
Common exposures come from the use of DEHP as a fragrance carrier in cosmeticsdehp full form, personal care products, laundry detergentscolognes, scented candlesand air fresheners. In utero exposure to di- 2-ethylhexyl phthalate decreases mineralocorticoid receptor expression in the adult testis.
If you have any questions, comments, or concerns about the content of this page, please contact us. Di 2-ethylhexyl phthalate DEHP. DEHP is on the Proposition 65 list because it can cause cancer and birth defects or other reproductive harm. Exposure to DEHP may increase the risk of cancer, and may also harm the male reproductive system. Exposure to DEHP during pregnancy may affect the development of the child. Proposition 65 requires businesses to determine if they must provide a warning about exposure to listed chemicals. What is DEHP?
Chemical Classification: Phthalates. Summary: Di 2-ethylhexyl phthlate DEHP is a manufactured chemical that is commonly added to plastics to make them flexible. DEHP is a colorless liquid with almost no odor. DEHP is present in plastic products such as wall coverings, tablecloths, floor tiles, furniture upholstery, shower curtains, garden hoses, swimming pool liners, rainwear, baby pants, dolls, some toys, shoes, automobile upholstery and tops, packaging film and sheets, sheathing for wire and cable, medical tubing, and blood storage bags. ToxFAQs - Fact sheet that answers the most frequently asked questions about a contaminant and its health effects. Toxicological Profile - Succinctly characterizes the toxicologic and adverse health effects information for a hazardous substance. ToxGuide pdf icon [ KB] - Quick reference guide providing information such as chemical and physical properties, sources of exposure, routes of exposure, minimal risk levels, children's health, and health effects for a substance.
Dehp full form
Federal government websites often end in. The site is secure. Diethylhexyl phthalate DEHP is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal care products. Due to the overuse of DEHP in many products, it enters and pollutes the environment through release from industrial settings and plastic waste disposal sites. DEHP can enter the body through inhalation, ingestion, and dermal contact on a daily basis, which has raised some concerns about its safety and its potential effects on human health. The main aim of this review is to give an overview of the endocrine, testicular, ovarian, neural, hepatotoxic, and cardiotoxic effects of DEHP on animal models and humans in vitro and in vivo.
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Exposure to DEHP has been associated with lower plasma thyroxine levels and decreased uptake of iodine in thyroid follicular cells. Scientific Reports. Journal of Chromatography A. Kim S. How does exposure to DEHP occur? Wipe up dust regularly, using a damp cloth. Christopher Download as PDF Printable version. DEHP belongs to a family of chemicals called phthalates, which are added to some plastics to make them flexible. Agarwal D. CFCT recommend that users should first wear socks to avoid direct skin contact. Explosive limits. People, especially children, may also be exposed by swallowing contaminated dust particles.
Context - Diethylhexyl-phthalate DEHP is a substance that is mainly used as an additive in plastics to make them more flexible.
Exposure of hemodialysis patients to diethylhexyl phthalate. Prenatal phthalate exposure has been shown to be associated with lower levels of reproductive function in adolescent males. Perinatal exposure to di- 2-ethylhexyl phthalate affects anxiety- and depression-like behaviors in mice. Kim S. Yamaguchi S. CAS Number. Phthalates induce neurotoxicity affecting locomotor and thermotactic behaviors and AFD neurons through oxidative stress in Caenorhabditis elegans. Effects of chronic phthalate exposure on the kidney. DEHP can enter the body through inhalation, ingestion, and dermal contact on a daily basis, which has raised some concerns about its safety and its potential effects on human health. Lactational exposure to DEHP disrupted glucose oxidation in the cardiac muscles of F1 female albino rats [ 90 ]. This includes an uncoupling effect that leads to irregular rhythms in vitro. DEHP exposure can lead to Se deficiency and an increase in oxidative stress in rat hepatocytes [ 85 ]. N verify what is Y N?
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