Balzac plus

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Last updated on Balzak plus is indicated in adult patients whose blood pressure is not adequately controlled on the combination of olmesartan medoxomil and amlodipine taken as dual-component formulation. Balzak plus is indicated as substitution therapy in adult patients whose blood pressure is adequately controlled on the combination of olmesartan medoxomil, amlodipine and hydrochlorothiazide, taken as a dual-component olmesartan medoxomil and amlodipine or olmesartan medoxomil and hydrochlorothiazide and a single-component formulation hydrochlorothiazide or amlodipine. A step-wise titration of the dosage of the individual components is recommended before changing to the triple-component combination. When clinically appropriate, direct change from dual-component combination to the triple-component combination may be considered. Patients controlled on stable doses of olmesartan medoxomil, amlodipine and hydrochlorothiazide taken at the same time as a dual-component olmesartan medoxomil and amlodipine or olmesartan medoxomil and hydrochlorothiazide and a single-component formulation hydrochlorothiazide or amlodipine may be switched to Balzak plus containing the same component doses.

Balzac plus

Amlodipine is a calcium ion influx inhibitor of the dihydropyridine group slow channel blocker or calcium ion antagonist and inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle. Olmesartan medoxomil is a potent, orally active, selective angiotensin II receptor type AT 1 antagonist. It is expected to block all actions of angiotensin II mediated by the AT 1 receptor, regardless of the source or route of synthesis of angiotensin II. The selective antagonism of the angiotensin II AT 1 receptors results in increases in plasma renin levels and angiotensin I and II concentrations, and some decrease in plasma aldosterone concentrations. Hydrochlorothiazide is a diuretic with antihypertensive properties. It acts by inhibiting the renal tubular re-absorption of sodium and chloride ions, which are excreted with an accompanying volume of water. Potassium excretion is also promoted. This drug has been classified in the anatomical therapeutic chemical ATC classification system as follows:. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles. Read about Amlodipine. Read about Olmesartan medoxomil. Read about Hydrochlorothiazide. Discover more medicines within C09DX Identifier s : , , , , , BE, BE

Increases in cholesterol and triglyceride levels are undesirable effects known to be associated with thiazide diuretic therapy.

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Amlodipine is a Dihydropyridine Calcium antagonist that inhibits the transmembrane influx of Calcium ions into cardiac and vascular smooth muscle. It has greater affinity towards vascular smooth muscle than on cardiac muscle. Amlodipine is peripheral vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascular resistance and thereby reduces blood pressure. Amlodipine reduces tone, decreases coronary vasoreactivity and lowers cardiac oxygen demand by reducing after load. Amlodipine has a strong affinity for cell membranes, modulating calcium influx by inhibiting selected membrane calcium channels.

Balzac plus

HTA esencial. Segundo y tercer trimestre del embarazo. Aldosteronismo primario. Riesgo de hiperpotasemia, especialmente en I.

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In patients whose vascular tone and renal function depend predominantly on the activity of the renin-angiotensin-aldosterone system e. Balzak plus should therefore be administered with caution in these patients. Renal impairment and kidney transplantation: When Balzak plus is used in patients with impaired renal function, periodic monitoring of serum concentrations of potassium and creatinine is recommended. The half-life of hydrochlorothiazide is prolonged in patients with impaired renal function. Add-on therapy Balzak plus is indicated in adult patients whose blood pressure is not adequately controlled on the combination of olmesartan medoxomil and amlodipine taken as dual-component formulation. Art History. As with other angiotensin II receptor antagonists, the coadministration of Balzak plus and lithium is not recommended. Returns offered from mainland France. Since a large proportion of olmesartan is excreted via the biliary route, use in patients with biliary obstruction is contraindicated. Reset password. Thiazides, including hydrochlorothiazide, can cause fluid or electrolyte imbalance including hypokalaemia, hyponatraemia and hypochloraemic alkalosis. Unlock exclusive artist performance data.

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Patients with primary aldosteronism generally will not respond to anti-hypertensive medicinal products acting through inhibition of the renin-angiotensin system. The information provided in Effects on ability to drive and use machines of Balzak plus is based on data of another medicine with exactly the same composition as the Balzak plus. Given their similar pharmacodynamic properties, these results are also relevant for other ACE-inhibitors and angiotensin II receptor blockers. The European Medicines Agency has waived the obligation to submit the results of studies with Balzak plus in all subsets of the paediatric population in essential hypertension. Patients controlled on stable doses of olmesartan medoxomil, amlodipine and hydrochlorothiazide taken at the same time as a dual-component olmesartan medoxomil and amlodipine or olmesartan medoxomil and hydrochlorothiazide and a single-component formulation hydrochlorothiazide or amlodipine may be switched to Balzak plus containing the same component doses. ACE-inhibitors and angiotensin II receptor blockers should not be used concomitantly in patients with diabetic nephropathy. The information provided in Undesirable effects of Balzak plus is based on data of another medicine with exactly the same composition as the Balzak plus. A step-wise titration of the dosage of the individual components is recommended before changing to the triple-component combination. The Princess and the Unicorn , Complete your basket. Last updated on Latent diabetes mellitus may become manifest during thiazide therapy. Name of the medicinal product.