Apoprotein
Apoproteins are the proteins of lipoproteins. The functions of several are known to regulate lipolytic enzyme activities and lipoprotein uptake into cells, apoprotein. The effects of overweight were studied on the apoprotein of production and removal of some of these proteins.
Apolipoproteins are proteins that bind lipids oil-soluble substances such as fats, cholesterol and fat soluble vitamins to form lipoproteins. They transport lipids in blood, cerebrospinal fluid and lymph. The lipid components of lipoproteins are insoluble in water. However, because of their detergent-like amphipathic properties, apolipoproteins and other amphipathic molecules such as phospholipids can surround the lipids, creating a lipoprotein particle that is itself water-soluble, and can thus be carried through body fluids i. In addition to stabilizing lipoprotein structure and solubilizing the lipid component, apolipoproteins interact with lipoprotein receptors and lipid transport proteins, thereby participating in lipoprotein uptake and clearance. They also serve as enzyme cofactors for specific enzymes involved in the metabolism of lipoproteins. Apolipoproteins are also exploited by hepatitis C virus HCV to enable virus entry, assembly, and transmission.
Apoprotein
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Publication types Research Support, apoprotein, Non-U. ApoA-IV synthesized in hypothalamus is apoprotein to be a satiating factor which regulate the food intake of the rodent. The Journal of Biological Chemistry.
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Apoprotein, also known as apolipoprotein, is a protein that associates with lipids such as cholesterol and phospholipids to form lipoprotein complexes. Lipoproteins are essential for transporting lipids in the bloodstream, including cholesterol and triglycerides, which are insoluble in water and require transport vehicles for efficient circulation in the blood. Apoprotein, also known as apolipoprotein, is a protein component found in association with lipids, particularly in the context of lipoprotein complexes. These proteins are essential for the transportation of lipids, including cholesterol and triglycerides, in the bloodstream. Apoproteins play crucial roles in lipid metabolism, including facilitating the assembly, stabilization, and recognition of lipoproteins, as well as regulating enzyme activity involved in lipid processing. In essence, apoproteins are protein components of lipoproteins that enable the efficient transport and metabolism of lipids throughout the body.
Apoprotein
Apolipoproteins are proteins that bind lipids oil-soluble substances such as fats, cholesterol and fat soluble vitamins to form lipoproteins. They transport lipids in blood, cerebrospinal fluid and lymph. The lipid components of lipoproteins are insoluble in water. However, because of their detergent-like amphipathic properties, apolipoproteins and other amphipathic molecules such as phospholipids can surround the lipids, creating a lipoprotein particle that is itself water-soluble, and can thus be carried through body fluids i. In addition to stabilizing lipoprotein structure and solubilizing the lipid component, apolipoproteins interact with lipoprotein receptors and lipid transport proteins, thereby participating in lipoprotein uptake and clearance. They also serve as enzyme cofactors for specific enzymes involved in the metabolism of lipoproteins. Apolipoproteins are also exploited by hepatitis C virus HCV to enable virus entry, assembly, and transmission. They play a role in viral pathogenesis and viral evasion from neutralizing antibodies.
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Exchangeable apolipoproteins apoA, apoC, and apoE have the same genomic structure and are members of a multi-gene family that probably evolved from a common ancestral gene. ApoB is an integral apoprotein whereas the others are peripheral apoproteins. Basic amino acids important for LDL receptor binding are clustered into a surface patch on one long helix. Download as PDF Printable version. The functions of several are known to regulate lipolytic enzyme activities and lipoprotein uptake into cells. Neurobiology of Aging. Journal of Pain Research. Apolipoprotein F apoF is one of the minor apolipoprotein in blood plasma and it is a lipid transfer inhibit protein to inhibit cholesteryl ester transfer protein-mediated transfers of cholesteryl esters and triglycerides. Clinical Chemistry and Laboratory Medicine. Since a major function of apo-AI and of HDL is to transport cholesterol, the increased production of HDL particles in terms of proteins , is consistent with the increased need to transport additional cholesterol which is a feature of obesity. Toggle limited content width. June
It is commonly used to detect risk of atherosclerotic cardiovascular disease. Apolipoprotein B is the primary apolipoprotein of chylomicrons , VLDL , Lp a , IDL , and LDL particles LDL—commonly known as "bad cholesterol " when in reference to both heart disease and vascular disease in general , which is responsible for carrying fat molecules lipids , including cholesterol , around the body to all cells within all tissues.
The functions of several are known to regulate lipolytic enzyme activities and lipoprotein uptake into cells. They play a role in viral pathogenesis and viral evasion from neutralizing antibodies. For example, apoA5 is also known as apo A-V. Basic amino acids important for LDL receptor binding are clustered into a surface patch on one long helix. Apolipoproteins are also exploited by hepatitis C virus HCV to enable virus entry, assembly, and transmission. ApoB is an integral apoprotein whereas the others are peripheral apoproteins. The Journal of Biological Chemistry. Journal of Proteomics. ApoE has been implicated in dementia and Alzheimer's disease. Contents move to sidebar hide. Category : Apolipoproteins. Apolipoprotein D apoD is a soluble carrier protein of lipophilic molecules in neurons and glial cells within the central and peripheral nervous system and apoD can also modulate the stability and oxidation status of these molecules. Apoproteins are the proteins of lipoproteins.
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